Enriching the Circadian Proteome
نویسندگان
چکیده
منابع مشابه
Circadian Orchestration of the Hepatic Proteome
Circadian rhythms are essential to health. Their disruption is associated with metabolic diseases in experimental animals and man. Local metabolic rhythms represent an output of tissue-based circadian clocks. Attempts to define how local metabolism is temporally coordinated have focused on gene expression by defining extensive and divergent "circadian transcriptomes" involving 5%-10% of genes a...
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Clock-generated biological rhythms provide an adaptive advantage to an organism, resulting in increased fitness and survival. To better elucidate the plant response to the circadian system, we surveyed protein oscillations in Arabidopsis seedlings under constant light. Using large-scale two-dimensional difference in gel electrophoresis (2D-DIGE) the abundance of more than 1000 proteins spots wa...
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The rich mammalian cellular circadian output affects thousands of genes in many cell types and has been the subject of genome-wide transcriptome and proteome studies. The results have been enigmatic because transcript peak abundances do not always follow the peaks of gene-expression activity in time. We posited that circadian degradation of mRNAs and proteins plays a pivotal role in setting the...
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Wheat, the "Staff of Life", has been an essential commodity to human existence through the centuries and is currently the most widely consumed staple food (Bagriansky, 2002). As versatile as they are nutritious, wheat products have graced tables in all continents. The range of forms this staple food takes is correspondingly varied: crusty French bread, soft Mexican tortillas and spicy Indonesia...
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ژورنال
عنوان ژورنال: Cell Metabolism
سال: 2017
ISSN: 1550-4131
DOI: 10.1016/j.cmet.2016.12.014